Membership of the Independent Scientific Advisory Committee (ISAC)

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Membership of the Independent Scientific Advisory Committee from 12 March 2009.

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Professor Jennifer Adgey (Chair)
Hon Prof Cardiology Queens University & Hon consultant cardiology, Royal Victoria Hospital,Belfast

Professor Jacqueline Cassell
Professor Jacqueline Cassell, Professor of Primary Care Epidemiology, Honorary Consultant in Health Protection and in Genitourinary Medicine, Brighton and Sussex Medical School

Professor Corinne De Vries
Professor of Pharmacoepidemiology, Department of Pharmacy and Pharmacology, University of Bath

Professor Richard Donnelly
Associate Dean & Professor of Vascular Medicine, University of Nottingham Medical School

Professor Martin Gulliford
Professor in Public Health at King's College London

Professor Amrit (Pali) Hungin
GP, Professor of Primary Care and General Practice and Dean of Medicine and Head of School of Health at the University of Durham

Dr Umesh T Kadam
GP Epidemiologist, Research Institute for Primary Care and Health Sciences, Keele University

Professor Paul Little
GP and Prof of Primary Care Research at the Aldermoor Health Centre, Southampton University

Dr David Lovell
Reader in Medical Statistics, University of Surrey

Professor Richard Martin
Professor in Clinical Epidemiology, Department of Social Medicine, University of Bristol

Dr Sarah Meredith (Deputy Chair)
Medical Research Council (MRC) Clinical Trials Unit

Professor Simon Mitchell
Consultant Neonatal Paediatrician St Mary’s Hospital Manchester, Honorary Professor, School of Health Care Professions, University of Salford

Professor Barbara Pierscionek
Lay member and Professor of Vision Science, University of Ulster

Ms Marcia Saunders
Lay member and lay member of the Royal Pharmaceutical Society of Great Britain

Dr Richard Stevens
Senior Statistician, Division of Public Health and Primary Care, University of Oxford

Dr Ruben Thanacoody
Consultant Physician, Royal Victoria Infirmary, Newcastle Upon Tyne Hospitals NHS Trust
Consultant Clinical Toxicologist, NPIS (Newcastle) and YCC (Northern and Yorkshire), Regional Drugs and Therapeutics Centre Honorary Senior Lecturer in Clinical Pharmacology, University of Newcastle-upon-Tyne


The ISAC uses a two team system for reviewing GPRD protocols. The composition of the 2 teams is as follows:

Team 1


Professional members

  • Professor Jacqueline Cassell
  • Professor Corrine De Vries
  • Professor Pali Hungin
  • Professor Richard Martin
  • Professor Simon Mitchell
  • Dr. Ruben Thanacoody
  • Dr. David Lovell

Lay Member

  • Professor Barbara Pierscionek

Team 2


Professional members

  • Professor Richard Donnelly
  • Professor Martin Gulliford
  • Professor Paul Little
  • Dr. Sarah Meredith
  • Dr. Umesh Kadam
  • Dr. Richard Stevens

Lay Member

  • Ms. Marcia Saunders

Please click on the following links to download or view the Independent Scientific Advisory Committee (ISAC) for MHRA database research Summary Minutes  or Annual Reports .